Build a scored GRanges object from a GRanges object and a single BigWig file. The aggregating function can be min, max, sd, mean.
Usage
.bw_ranges(
bwfile,
granges,
per_locus_stat = "mean",
selection = NULL,
default_na = NA_real_,
scaling = "none"
)Arguments
- bwfile
Path to a single BigWig file to be summarized.
- granges
GRanges object file to be summarized.
- per_locus_stat
Aggregating function (per locus). Mean by default. Choices: min, max, sd, mean.
- selection
A GRanges object to restrict binning to a certain set of intervals. This is useful for debugging and improving performance of locus specific analyses.
- default_na
Default value for missing values
- scaling
If none, no operation is performed (default). If relative, values are divided by global mean (1x genome coverage).